| Title | Genre | Company |
|---|---|---|
| Q Billion | Puzzle | SETA Corporation |
| Q-Bert | unknown | |
| Q*Bert 3 | Puzzle | Realtime Associates |
| QBasic Gorillas | Strategy | Microsoft Corporation |
| Qin - The Tomb of the Middle Kingdom | Adventure | Time Warner Interactive |
| Qink | unknown | |
| Qix | Action | Taito |
| Qrax (aka Prometheus) | Action | Quarter Note Software |
| QuackMan | Action | David S. Shelley |
| QuackShot starring Donald Duck | Action | Sega Corporation |
| Quad | Action | Nick Sumner |
| Quadralien | unknown | |
| Quadrax | Puzzle | Cauldron |
| Quadrel | Puzzle | Loriciel |
| Quagmire | Action | CelluSoft |
| Quake | unknown | id software |
| Quake 2 | Misc | Id |
| Quake 4 | Action | Aspyr |
| Quake III Arena | Action | Activision |
| Quake: MacNehahra 1.1b3 - Game Expansion | Action | The Nehahra Project |
| Quandaries | unknown | |
| Quantum Fighter | unknown | |
| Quantum Gate | Adventure | HyperBole Studios |
| Quarantine | Sport | GameTek |
| Quarantine 2 - Road Warrior | Action | GameTek |
| Quark | Action | Spencer Seidel |
| Quarky & Quaysoo';s Turbo Science | Educational | Sierra |
| Quarter Back | unknown | |
| QuarterPole | Simulation | Microleague Interactive Software |
| Quarters | Puzzle | Sperling Corporation |
| Quarterstaff | RPG | Simulated Environment Systems |
| Quarterstaff: The Tomb of Setmoth | Adventure | Amy Briggs |
| Quarto | Puzzle | Alan Weiss |
| Quartzeroids 2 | Action | John-Michael Mulesa |
| Quasar Wars | Action | Light Design |
| Quasimodo | Action | Synapse Software |
| Quazatron | Action | Graftgold |
| Quedex | Action | Thalamus |
| Queen Quest | Adventure | Caleb J. Emmons |
| Quelle | Puzzle | Caleb J. Emmons |
| Querkz | Puzzle | Adam Winiecki |
| Quest | Adventure | Commodore |
| Quest 2: The Forest Trap | unknown | MVD Software |
| Quest for Camelot | Strategy | Funnybone Interactive |
| Quest for Glory - Shadows of Darkness | unknown | Sierra |
| Quest for Glory [remake] | Adventure | Sierra |
| Quest For Glory 1 - So you want to be a Hero | unknown | Sierra |
| Quest for Glory 1: So You Want To Be A Hero | Adventure | Sierra On‑Line, Inc. |
| Quest for Glory 2 - Trial By Fire | Adventure | Sierra |
| Quest for Glory 2: Trial by Fire - Remake | Adventure | AGD Interactive |
| Quest For Glory 3 - Wages of War | unknown | Sierra |
| Quest for Glory V: Dragon Fire | Adventure | Sierra |
| Quest for the Dark Sword | Adventure | Iain Becker |
| Quest for The Timebird | Adventure | Firebird |
| Quest for Water Safety: A Wizardly Adventure | Educational | Northstar Communications |
| Quest Of Garnath | Adventure | Public Domain |
| Quest Of Yipe! | RPG | Kevin Kinell |
| Quest: The Dungeon Escape | unknown | Michael Duhm |
| Questmaster I - The Prism Of Heheutotol | Adventure | Miles Computing |
| Questprobe 1 - The Incredible Hulk (Disk Version) | Adventure | Adventure International |
| Questprobe 2 - Spider Man (Disk Version) | Adventure | Adventure International |
| Questprobe 3 - Fantastic Four (Disk Version) | Adventure | Adventure International |
| Questron | Adventure | SSI |
| Questron 2 | RPG | Strategic Simulations Inc. |
| Quick Majik Adventure | RPG | Neurosport |
| Quick the Thunder Rabbit | Action | Titus |
| QuickShot Deluxe | Action | Jim Plamondon |
| QuickSLIP | Action | Robert Chancellor |
| Quien mato a Brett Penance - El Caso del Surfista Ecologista | unknown | System 4 |
| Quink | Strategy | CBS Software |
| Quinn | Puzzle | Simon Härtel |
| Quintette | Puzzle | Michael McNally |
| Quiver | Action | |
| Quo Vadis | Puzzle | Andrea Pellizzon |
| Qwirks | Puzzle | Big Bang Software |